Job Description

Base Pay Range

$150,000.00/yr - $190,000.00/yr

The heart of Prellis Bio s strategy is the combination of novel, cuttingedge methods in machine learning, biology at scale, and nextgen antibody discovery that address longstanding industrywide problems in the drug development pipeline. Prellis Biologics uses proprietary technology to 3D print human lymph node organoids, enabling the rapid and diverse discovery of human antibody therapeutic candidates for a range of applications. To drive this forward, we are assembling an incredible team of discovery biologists, computational scientists, and protein scientists who want to make a difference to this important problem.

Position Summary

We are seeking a highly motivated Senior/Principal Scientist Next Generation Sequencing (NGS) to drive our biotherapeutic discovery efforts and technological advancements. This pivotal role involves:

• Implementing cuttingedge NGS and molecular techniques for rapid discovery of novo antibody candidates.
• Driving strategic innovation by shaping the future of our discovery platforms.
• Collaborating across functions and providing effective leadership and mentorship within the NGS team.

Responsibilities

• Lead the strategic planning and execution of NGSenabled discovery campaigns.
• Drive capability building and technology innovation (e.g., CITESeq, automation).
• Partner with the bioinformatician to ensure effective dissemination of experimental results, driving datainformed decisionmaking.
• Collaborate with Data Science team to establish robust data pipelines and support AI/ML projects.
• Leverage crossfunctional collaboration to accelerate lead identification.
• Empower team members through mentorship to achieve measurable capability improvement.

Qualifications

• Ph.D. and relevant postdoctoral experience in Molecular Biology and Immunology, and 3+ years (Senior Scientist) or 5+ years (Principal Scientist) of relevant experience with expanding scientific capabilities and professional development.
• Demonstrated experience in leading highperforming teams (23 people).
• Broad knowledge in therapeutic antibody discovery pipeline with handson experience in antibody sequencing technologies (e.g., single B cells, bulk BCR repertoire, 10xGenomics).
• Deep knowledge in antibody repertoire biology and sequence attributes.
• Exceptional interpersonal and communication skills in a collaborative environment.
• Strong organizational skills, attention to detail, and ability to drive multiple projects.
• Demonstrated experience in collaborating across various scientific disciplines in a dynamic environment.

Bonus Experience

• Familiarity with automated liquid handlers or highthroughput molecular biology workflows.
• Working knowledge in displaybased discovery techniques.
• Keen interest in AI/ML driven discovery, protein optimization, and attribute prediction.

About Prellis

Prellis Biologics is a preIPO biotech located in Berkeley, CA with a teamoriented, inclusive, and familyfriendly culture. Our growing pipeline targets high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celestia, Khosla Ventures, SOSV, and Avidity Partners.

Benefits

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and wellbeing. From our competitive benefits to our collaborative culture, well support your journey every step of the way.

• A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts, and a 401(k) plan.
• Stockbased longterm incentives.
• Holiday package including a 1+ week winter shutdown.
• Flexible work models, including remote and hybrid working arrangements, where possible.

Application Process

Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Equal Opportunity Statement

Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teamsgrounded in a wide range of expertise and life experiencesand work even harder to ensure those teams thrive in inclusive, growthoriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

Seniority Level

MidSenior level

Employment Type

Fulltime

Job Function

Research

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