Job Title : Principal Scientist, Biophysics Location: Cambridge, MA About the Job Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. We are seeking a highly skilled and experienced Principal Scientist specializing in Biophysics to join our U.S. IDD Structural biology and Biophysics group. The successful candidate will lead cutting-edge small-molecule research projects, applying advanced biophysical techniques to support drug discovery and development efforts. This will be a lab-based role. We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started? Main Responsibilities: Lead complex biophysical research projects in support of small-molecule drug discovery programs. Design and execute experiments using a wide range of biophysical techniques, including but not limited to: Surface Plasmon Resonance (SPR), Isothermal Titration Calorimetry (ITC), Circular Dichroism (CD), DSF, MST, Fluorescence spectroscopy. Analyze and interpret complex biophysical data to provide insights into protein-ligand interactions, protein structure, and drug mechanism of action. Collaborate closely with multidisciplinary teams, including medicinal chemists, structural biologists, biochemists, computational scientists, and therapeutic area scientists. Work closely with cell biology to enable in vitro/in vivo correlation. Stay current with the latest advancements in biophysical techniques and implement new methodologies as appropriate. Author scientific publications and present research findings at internal meetings and external conferences. About You Qualifications: Ph.D., M.S. in Biophysics, Biochemistry, or a closely related field. Minimum of 7-9 years of experience in biophysics, with a strong track record in the pharmaceutical or biotechnology industry. Extensive hands-on experience with a wide range of biophysical techniques and instrumentation. Proven ability to lead complex research projects and collaborate effectively in a multidisciplinary environment. Strong analytical and problem-solving skills with the ability to interpret complex data sets. Excellent communication skills, both written and verbal. Track record of scientific publications in peer-reviewed journals and presentations at international conferences. Key Competencies: Scientific leadership and innovation, Project management, Collaborative teamwork, Analytical thinking and problem-solving, Effective communication and presentation skills. This role offers an exciting opportunity to contribute to groundbreaking research in drug discovery, working at the forefront of biophysical sciences in a dynamic, collaborative environment at Sanofi. Why Choose Us? Bring the miracles of science to life alongside a supportive, future-focused team. Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs, and at least 14 weeks’ gender-neutral parental leave. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #J-18808-Ljbffr Sanofi
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